The presence of traditional and nontraditional risk factors that frequently coexist with type 2 diabetes. Abstract: Individuals with type 2 diabetes have a two to four fold increased risk for developing cardiovascular disease than persons without diabetes. TI - Agreement between Framingham Risk Score and United Kingdom Prospective Diabetes Study Risk Engine in Identifying High Coronary Heart Disease Risk in North Indian PopulationĪB - Background: The aim of the study is to evaluate the concurrence between Framingham Risk score (FRS) and United Kingdom Prospective Diabetes Study (UKPDS) risk engine in identifying coronary heart disease (CHD) risk in newly detected diabetes mellitus patients and to explore the characteristics associated with the discrepancy between them. Keywords: Cardiovascular risk, Diabetes mellitus, UKPDS risk engine, Diabetes PHD, DECODE. However, longitudinal follow-up is required to form firm conclusions. The UK Prospective Diabetes Study (UKPDS) Risk Engine is a type 2 diabetes-specific risk calculator that includes A1C as well as traditional CVD risk factors. The concurrence of a number of factors (e.g., male sex, low high density lipoprotein cholesterol, and smoking) in both algorithms should be regarded as increasing the CHD risk. Patients with high risk on UKPDS but not FRS were males and have high glycosylated hemoglobin.Ĭonclusion: The FRS and UKPDS (threshold 20%) identified different populations as being at high risk, though the agreement between them was fairly good. Analysis showed that subjects having high risk on FRS but not UKPDS were elderly females having raised systolic and diastolic blood pressure. A total of 7,067 patients without CHD at baseline were. The United Kingdom Prospective Diabetes Study (UKPDS) risk engine calculates. This study aimed to validate the UKPDS risk engine and, if indicated, develop CHD risk scores. The best agreement was observed at high-risk threshold of 20% for both (κ=0.463). Understanding a patients 10-year ASCVD risk is fundamental in establishing. About 9.4% had high risk by UKPDS but not FRS, and 8.6% had high risk by FRS but not UKPDS. Discrepancy was observed in 17.9% (range, 14.7 to 21.7) subjects. Results: The FRS identified 20.9% subjects (range, 17.5 to 24.7) as high-risk while UKPDS identified 21.75% (range, 18.3 to 25.5) as high-risk. Subjects with discrepant scores between two algorithms were identified and associated variables were determined. Agreement between FRS and UKPDS in classifying patients as high risk was calculated using kappa statistic. Methods: A cross-sectional study involving 489 subjects newly diagnosed with type 2 diabetes mellitus was conducted. Results: Sex, age, HbA1c, years after diagnosis, BMI, systolic blood pressure, non-HDL cholesterol, albumin-to-creatinine ratio, atrial fibrillation, current smoker, and leisure-time physical activity were risk factors for macro- and microvascular. Background: The aim of the study is to evaluate the concurrence between Framingham Risk score (FRS) and United Kingdom Prospective Diabetes Study (UKPDS) risk engine in identifying coronary heart disease (CHD) risk in newly detected diabetes mellitus patients and to explore the characteristics associated with the discrepancy between them. Unlike other tools, the UKPDS risk engine is diabetes-specific and it incorporates glycemia, systolic blood pressure (SBP), and lipid levels as risk factors. Objective: To develop and validate a risk engine that calculates the risks of macro- and microvascular complications in type 2 diabetes. If your question remains unanswered, Email. Contact usįor queries concerning the UKPDS Risk Engine please read the FAQ. Full details of the equations used have been published. These can be calculated for any given duration of type 2 diabetes based on current age, sex, ethnicity, smoking status, presence or absence of atrial fibrillation and levels of HbA1c, systolic blood pressure, total cholesterol and HDL cholesterol.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |